Destiny 2’s Path of the Splicer is a questline running throughout Season of the Splicer.
Similar to Challenger’s Proving during Season of the Chosen, this provides structure to the season’s new activities and features, with each week tasking you with using the Splicer Gauntlet and opening chests in Override.
From week three onwards, you also have access to new Expunge missions, which are also required to be completed as part of the quest.